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Prevalence and risk factors of preoperative deep venous thrombosis in closed patella fracture: a prospective cohort study

BACKGROUND: The preoperative prevalence of deep venous thromboembolism (DVT) of patella fracture is not well established. The study aimed to investigate the preoperative prevalence, the associated risk factors, and the locations of deep venous thrombosis (DVT) in patients with closed patella fractur...

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Autores principales: Tan, Zhanchao, Hu, Hongzhi, Wang, Zhongzheng, Wang, Yuchuan, Zhang, Yingze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220698/
https://www.ncbi.nlm.nih.gov/pubmed/34162417
http://dx.doi.org/10.1186/s13018-021-02558-4
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author Tan, Zhanchao
Hu, Hongzhi
Wang, Zhongzheng
Wang, Yuchuan
Zhang, Yingze
author_facet Tan, Zhanchao
Hu, Hongzhi
Wang, Zhongzheng
Wang, Yuchuan
Zhang, Yingze
author_sort Tan, Zhanchao
collection PubMed
description BACKGROUND: The preoperative prevalence of deep venous thromboembolism (DVT) of patella fracture is not well established. The study aimed to investigate the preoperative prevalence, the associated risk factors, and the locations of deep venous thrombosis (DVT) in patients with closed patella fracture. METHODS: Patients who sustained closed patella fracture between January 1, 2016, and April 1, 2019, were included. Blood analyses and ultrasonography of bilateral lower extremities were routinely performed. Data of demographics, comorbidities, mechanism of injury, fracture type, total hospital stay, time from injury to DVT, and laboratory indexes were prospectively collected and compared between groups with and with non-DVT. Multivariate logistic regression analyses were performed to determine the independent risk factors of DVT. RESULTS: Among the study cohort of 790 patients, 35 cases occurred in preoperative DVTs, indicating a prevalence of 4.4%, with 3.2% distal and 1.2% proximal DVT. Age ≥ 65 years old (OR, 3.0, 95% CI, 1.1–8.1), D-dimer > 0.5 mg/L (OR, 2.3, 95% CI, 1.1–4.8), and albumin < 35 g/L (OR, 2.5, 95% CI, 1.2–5.3) were identified to be risk factors of DVT in closed patella fracture. Among the DVTs, 30 cases (85.7%) occurred in the injured extremity, 3 cases (8.6%) in bilateral extremities, and 2 cases (5.7%) solely in the uninjured extremity. CONCLUSION: The prevalence of preoperative DVT in closed patella fracture was 4.4%, with 3.2% for distal and 1.2% for proximal DVT. We recommend individualized risk stratification and early anticoagulation for patients with risk factors (age ≥ 65 years, D-dimer > 0.5 mg/L and albumin < 35g/L).
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spelling pubmed-82206982021-06-23 Prevalence and risk factors of preoperative deep venous thrombosis in closed patella fracture: a prospective cohort study Tan, Zhanchao Hu, Hongzhi Wang, Zhongzheng Wang, Yuchuan Zhang, Yingze J Orthop Surg Res Research Article BACKGROUND: The preoperative prevalence of deep venous thromboembolism (DVT) of patella fracture is not well established. The study aimed to investigate the preoperative prevalence, the associated risk factors, and the locations of deep venous thrombosis (DVT) in patients with closed patella fracture. METHODS: Patients who sustained closed patella fracture between January 1, 2016, and April 1, 2019, were included. Blood analyses and ultrasonography of bilateral lower extremities were routinely performed. Data of demographics, comorbidities, mechanism of injury, fracture type, total hospital stay, time from injury to DVT, and laboratory indexes were prospectively collected and compared between groups with and with non-DVT. Multivariate logistic regression analyses were performed to determine the independent risk factors of DVT. RESULTS: Among the study cohort of 790 patients, 35 cases occurred in preoperative DVTs, indicating a prevalence of 4.4%, with 3.2% distal and 1.2% proximal DVT. Age ≥ 65 years old (OR, 3.0, 95% CI, 1.1–8.1), D-dimer > 0.5 mg/L (OR, 2.3, 95% CI, 1.1–4.8), and albumin < 35 g/L (OR, 2.5, 95% CI, 1.2–5.3) were identified to be risk factors of DVT in closed patella fracture. Among the DVTs, 30 cases (85.7%) occurred in the injured extremity, 3 cases (8.6%) in bilateral extremities, and 2 cases (5.7%) solely in the uninjured extremity. CONCLUSION: The prevalence of preoperative DVT in closed patella fracture was 4.4%, with 3.2% for distal and 1.2% for proximal DVT. We recommend individualized risk stratification and early anticoagulation for patients with risk factors (age ≥ 65 years, D-dimer > 0.5 mg/L and albumin < 35g/L). BioMed Central 2021-06-23 /pmc/articles/PMC8220698/ /pubmed/34162417 http://dx.doi.org/10.1186/s13018-021-02558-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Tan, Zhanchao
Hu, Hongzhi
Wang, Zhongzheng
Wang, Yuchuan
Zhang, Yingze
Prevalence and risk factors of preoperative deep venous thrombosis in closed patella fracture: a prospective cohort study
title Prevalence and risk factors of preoperative deep venous thrombosis in closed patella fracture: a prospective cohort study
title_full Prevalence and risk factors of preoperative deep venous thrombosis in closed patella fracture: a prospective cohort study
title_fullStr Prevalence and risk factors of preoperative deep venous thrombosis in closed patella fracture: a prospective cohort study
title_full_unstemmed Prevalence and risk factors of preoperative deep venous thrombosis in closed patella fracture: a prospective cohort study
title_short Prevalence and risk factors of preoperative deep venous thrombosis in closed patella fracture: a prospective cohort study
title_sort prevalence and risk factors of preoperative deep venous thrombosis in closed patella fracture: a prospective cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220698/
https://www.ncbi.nlm.nih.gov/pubmed/34162417
http://dx.doi.org/10.1186/s13018-021-02558-4
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