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Comparative assessment of in vitro BBB tight junction integrity following exposure to cigarette smoke and e-cigarette vapor: a quantitative evaluation of the protective effects of metformin using small-molecular-weight paracellular markers
BACKGROUND: The blood–brain barrier (BBB) plays a critical role in protecting the central nervous system (CNS) from blood-borne agents and potentially harmful xenobiotics. Our group’s previous data has shown that tobacco smoke (TS) and electronic cigarettes (EC) affect the BBB integrity, increase st...
Autores principales: | Kadry, Hossam, Noorani, Behnam, Bickel, Ulrich, Abbruscato, Thomas J., Cucullo, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220771/ https://www.ncbi.nlm.nih.gov/pubmed/34158083 http://dx.doi.org/10.1186/s12987-021-00261-4 |
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