TPM, FPKM, or Normalized Counts? A Comparative Study of Quantification Measures for the Analysis of RNA-seq Data from the NCI Patient-Derived Models Repository

BACKGROUND: In order to correctly decode phenotypic information from RNA-sequencing (RNA-seq) data, careful selection of the RNA-seq quantification measure is critical for inter-sample comparisons and for downstream analyses, such as differential gene expression between two or more conditions. Sever...

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Detalles Bibliográficos
Autores principales: Zhao, Yingdong, Li, Ming-Chung, Konaté, Mariam M., Chen, Li, Das, Biswajit, Karlovich, Chris, Williams, P. Mickey, Evrard, Yvonne A., Doroshow, James H., McShane, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220791/
https://www.ncbi.nlm.nih.gov/pubmed/34158060
http://dx.doi.org/10.1186/s12967-021-02936-w

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