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Identification of two subtilisin‐like serine proteases engaged in the degradation of recombinant proteins in Nicotiana benthamiana
The tobacco variant Nicotiana benthamiana has recently emerged as a versatile host for the manufacturing of protein therapeutics, but the fidelity of many recombinant proteins generated in this system is compromised by inadvertent proteolysis. Previous studies have revealed that the anti‐HIV‐1 antib...
Autores principales: | Puchol Tarazona, Alejandro A., Maresch, Daniel, Grill, Annette, Bakalarz, Janet, Torres Acosta, Juan A., Castilho, Alexandra, Steinkellner, Herta, Mach, Lukas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221030/ https://www.ncbi.nlm.nih.gov/pubmed/33263189 http://dx.doi.org/10.1002/1873-3468.14014 |
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