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Identification of two subtilisin‐like serine proteases engaged in the degradation of recombinant proteins in Nicotiana benthamiana

The tobacco variant Nicotiana benthamiana has recently emerged as a versatile host for the manufacturing of protein therapeutics, but the fidelity of many recombinant proteins generated in this system is compromised by inadvertent proteolysis. Previous studies have revealed that the anti‐HIV‐1 antib...

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Detalles Bibliográficos
Autores principales: Puchol Tarazona, Alejandro A., Maresch, Daniel, Grill, Annette, Bakalarz, Janet, Torres Acosta, Juan A., Castilho, Alexandra, Steinkellner, Herta, Mach, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221030/
https://www.ncbi.nlm.nih.gov/pubmed/33263189
http://dx.doi.org/10.1002/1873-3468.14014

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