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GRSF1 deficiency in skeletal muscle reduces endurance in aged mice
GRSF1 is a mitochondrial RNA-binding protein important for maintaining mitochondrial function. We found that GRSF1 is highly expressed in cultured skeletal myoblasts differentiating into myotubes. To understand the physiological function of GRSF1 in vivo, we generated mice in which GRSF1 was specifi...
Autores principales: | Driscoll, Riley K., Krasniewski, Linda K., Cockey, Samuel G., Yang, Jen-Hao, Piao, Yulan, Lehrmann, Elin, Zhang, Yongqing, Michel, Marc, Noh, Ji Heon, Cui, Chang-Yi, Gorospe, Myriam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221292/ https://www.ncbi.nlm.nih.gov/pubmed/34078750 http://dx.doi.org/10.18632/aging.203151 |
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