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Age-related defects in autophagy alter the secretion of paracrine factors from bone marrow mononuclear cells

Bone marrow mononuclear cell therapy improves cardiac repair after myocardial infarction (MI), in-part through signaling to resident cardiac cells, such as fibroblasts, which regulate scar formation. The efficacy of cell therapy declines with age, as aging of both donor and recipient cells decreases...

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Detalles Bibliográficos
Autores principales:	Yeganeh, Azadeh, Alibhai, Faisal J., Tobin, Stephanie W., Lim, Fievel, Wu, Jun, Li, Shuhong, Weisel, Richard D., Li, Ren-Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221303/ https://www.ncbi.nlm.nih.gov/pubmed/34088884 http://dx.doi.org/10.18632/aging.203127

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