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Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging
Vascular dementia (VaD) is a progressive cognitive impairment of vascular etiology. VaD is characterized by cerebral hypoperfusion, increased blood-brain barrier permeability and white matter lesions. An increased burden of VaD is expected in rapidly aging populations. The hippocampus is particularl...
Autores principales: | Baik, Sang-Ha, Selvaraji, Sharmelee, Fann, David Y., Poh, Luting, Jo, Dong-Gyu, Herr, Deron R., Zhang, Shenpeng R., Kim, Hyun Ah, Silva, Michael De, Lai, Mitchell K.P., Chen, Christopher Li-Hsian, Drummond, Grant R., Lim, Kah-Leong, Sobey, Christopher G., Arumugam, Thiruma V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221317/ https://www.ncbi.nlm.nih.gov/pubmed/34074801 http://dx.doi.org/10.18632/aging.203123 |
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