Cargando…

Myeloid-specific SIRT1 deletion exacerbates airway inflammatory response in a mouse model of allergic asthma

Sirtuin 1 (SIRT1) is a class III histone deacetylase that exerts an anti-inflammatory effect in airway diseases. Activated macrophages play an important role in asthma. However, the roles of SIRT1 on allergic airway inflammation in macrophages remain largely unexplored. In this study, we aimed to de...

Descripción completa

Detalles Bibliográficos
Autores principales: Lai, Tianwen, Su, Guomei, Wu, Dong, Chen, Ziyu, Chen, Yujuan, Yi, Huajuan, Gao, Yun, Chen, Cuifen, Zeng, Man, Chen, Min, Li, Dongming, Wu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221322/
https://www.ncbi.nlm.nih.gov/pubmed/34099590
http://dx.doi.org/10.18632/aging.203104