Cargando…

Myeloid-specific SIRT1 deletion exacerbates airway inflammatory response in a mouse model of allergic asthma

Sirtuin 1 (SIRT1) is a class III histone deacetylase that exerts an anti-inflammatory effect in airway diseases. Activated macrophages play an important role in asthma. However, the roles of SIRT1 on allergic airway inflammation in macrophages remain largely unexplored. In this study, we aimed to de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lai, Tianwen, Su, Guomei, Wu, Dong, Chen, Ziyu, Chen, Yujuan, Yi, Huajuan, Gao, Yun, Chen, Cuifen, Zeng, Man, Chen, Min, Li, Dongming, Wu, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221322/ https://www.ncbi.nlm.nih.gov/pubmed/34099590 http://dx.doi.org/10.18632/aging.203104

Ejemplares similares

SIRT1 protects against urban particulate matter-induced airway inflammation
por: Lai, Tianwen, et al.
Publicado: (2019)

Myeloid-Specific SIRT6 Deletion Protects Against Particulate Matter (PM(2.5))-Induced Airway Inflammation
por: Chen, Shaopeng, et al.
Publicado: (2023)

YKL-40 expression in chronic obstructive pulmonary disease: relation to acute exacerbations and airway remodeling
por: Lai, Tianwen, et al.
Publicado: (2016)

Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling
por: Zhu, Yanlong, et al.
Publicado: (2022)

Exacerbation of allergic asthma by somatic antigen of Echinococcus granulosus in allergic airway inflammation in BALB/c mice
por: Ghabdian, Sara, et al.
Publicado: (2022)

Deletion of Miro1 in airway club cells potentiates allergic asthma phenotypes
por: Bruno, Sierra, et al.
Publicado: (2023)

Proline is increased in allergic asthma and promotes airway remodeling
por: Xu, Tingting, et al.
Publicado: (2023)

Application of vitamin E to antagonize SWCNTs-induced exacerbation of allergic asthma
por: Li, Jinquan, et al.
Publicado: (2014)

Epidemiology of Asthma and Allergic Airway Diseases
por: Devereux, Graham, et al.
Publicado: (2014)

Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation
por: Laanesoo, Anet, et al.
Publicado: (2021)

YKL-40 is correlated with FEV(1) and the asthma control test (ACT) in asthmatic patients: influence of treatment
por: Lai, Tianwen, et al.
Publicado: (2015)

Virus-Induced Asthma Exacerbations: SIRT1 Targeted Approach
por: Fukuda, Yosuke, et al.
Publicado: (2020)

Nerve growth factor exacerbates allergic lung inflammation and airway remodeling in a rat model of chronic asthma
por: YANG, YUN-GANG, et al.
Publicado: (2013)

Titanium Dioxide Nanoparticles Exacerbate Allergic Airway Inflammation via TXNIP Upregulation in a Mouse Model of Asthma
por: Lim, Je-Oh, et al.
Publicado: (2021)

Exacerbation of asthma and airway infection: is the virus the villain?()()
por: Costa, Lusmaia D.C., et al.
Publicado: (2014)

Exacerbation of asthma and airway infection: is the virus the villain?()()
por: Costa, Lusmaia D.C., et al.
Publicado: (2014)

Peripheral airways involvement in children with asthma exacerbation
por: Wawszczak, Maria, et al.
Publicado: (2021)

The HDAC10 instructs macrophage M2 program via deacetylation of STAT3 and promotes allergic airway inflammation
por: Zhong, Yu, et al.
Publicado: (2023)

IL‐33/ST2 axis deficiency exacerbates neutrophil‐dominant allergic airway inflammation
por: Ma, Qiyun, et al.
Publicado: (2021)

Targeted deletion of Interleukin-3 results in asthma exacerbations
por: Kölle, Julia, et al.
Publicado: (2022)

Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice
por: Cloots, Roy H. E., et al.
Publicado: (2017)

Metformin alleviates allergic airway inflammation and increases Treg cells in obese asthma
por: Guo, Yimin, et al.
Publicado: (2021)

Allergic Rhinitis, Asthma, and Rhinosinusitis: Diseases of the Integrated Airway
por: Meltzer, Eli O., et al.
Publicado: (2004)

Interleukin-31 expression and relation to disease severity in human asthma
por: Lai, Tianwen, et al.
Publicado: (2016)

Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation
por: Oikonomou, Nikos, et al.
Publicado: (2021)

Elevated expression of placental growth factor is associated with airway-wall vascular remodelling and thickening in smokers with asthma
por: Wu, Dong, et al.
Publicado: (2017)

Bergenin ameliorates airway inflammation and remodeling in asthma by activating SIRT1 in macrophages to regulate the NF-κB pathway
por: Huang, Dan, et al.
Publicado: (2022)

Role of liver-X-receptors in airway remodeling in mice with chronic allergic asthma
por: Zhang, Jinmei, et al.
Publicado: (2021)

Long-term efficacy and safety of omalizumab in patients with persistent uncontrolled allergic asthma: a systematic review and meta-analysis
por: Lai, Tianwen, et al.
Publicado: (2015)

Regulatory T Cells, a Viable Target Against Airway Allergic Inflammatory Responses in Asthma
por: Zhang, Jing, et al.
Publicado: (2022)

Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation
por: Dai, Bing, et al.
Publicado: (2023)

Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma
por: Tam, Anthony, et al.
Publicado: (2022)

Allergic rhinitis and asthma: inflammation in a one-airway condition
por: Jeffery, Peter K, et al.
Publicado: (2006)

Mechanistic insight into the impact of nanomaterials on asthma and allergic airway disease
por: Meldrum, Kirsty, et al.
Publicado: (2017)

Effect of neuromedin U on allergic airway inflammation in an asthma model
por: Ren, Xiaojie, et al.
Publicado: (2020)

Neuro-Immune Regulation in Inflammation and Airway Remodeling of Allergic Asthma
por: Zhang, Ning, et al.
Publicado: (2022)

Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma
por: Cloots, Roy H. E., et al.
Publicado: (2018)

Changes in airway diameter and mucus plugs in patients with asthma exacerbation
por: Yoshida, Yuki, et al.
Publicado: (2020)

Small Airway Dysfunction in Cough Variant Asthma: Prevalence, Clinical, and Pathophysiological Features
por: Yi, Fang, et al.
Publicado: (2022)

IRAK-M knockout promotes allergic airway inflammation, but not airway hyperresponsiveness, in house dust mite-induced experimental asthma model
por: Zhang, Xudong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s8aunros24niaej1pj093u1n5q