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Association of growth hormone receptor gene variant with longevity in men is due to amelioration of increased mortality risk from hypertension

The single nucleotide polymorphism (SNP) rs4130113 of the growth hormone receptor gene (GHR) is associated with longevity. Here we explored whether longevity-associated genotypes protect against mortality in all individuals, or only in individuals with aging-related diseases. Rs4130113 genotypes wer...

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Detalles Bibliográficos
Autores principales: Donlon, Timothy A., Chen, Randi, Masaki, Kamal H., Willcox, D. Craig, Allsopp, Richard C., Willcox, Bradley J., Morris, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221335/
https://www.ncbi.nlm.nih.gov/pubmed/34074802
http://dx.doi.org/10.18632/aging.203133