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Alterations in the RTK/Ras/PI3K/AKT pathway serve as potential biomarkers for immunotherapy outcome of diffuse gliomas

Background: Diffuse gliomas are the most common malignant brain tumors, and immune checkpoint inhibitors have limited therapeutic effects against this cancer. Three oncogenic pathways are altered in diffuse gliomas: the RTK/Ras/PI3K/AKT signaling, TP53, and RB pathways. Although these pathways may a...

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Detalles Bibliográficos
Autores principales:	Han, Song, Wang, Peng-Fei, Cai, Hong-Qing, Wan, Jing-Hai, Li, Shou-Wei, Lin, Ze-Huan, Yu, Chun-Jiang, Yan, Chang-Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221357/ https://www.ncbi.nlm.nih.gov/pubmed/34100771 http://dx.doi.org/10.18632/aging.203102

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