Cargando…

Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects

Wound healing is a multi-step process to rapidly restore the barrier function. This process is often impaired in diabetic patients resulting in chronic wounds and amputation. We previously found that paradoxical activation of the mitogen-activated protein kinase (MAPK) pathway via topical administra...

Descripción completa

Detalles Bibliográficos
Autores principales: Escuin-Ordinas, Helena, Liu, Yining, Sun, Lu, Hugo, Willy, Dimatteo, Robert, Huang, Rong Rong, Krystofinski, Paige, Azhdam, Ariel, Lee, Jordan, Comin-Anduix, Begoña, Cochran, Alistair J., Lo, Roger S., Segura, Tatiana, Scumpia, Philip O., Ribas, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221471/
https://www.ncbi.nlm.nih.gov/pubmed/34161353
http://dx.doi.org/10.1371/journal.pone.0252597