Cargando…
The role of let-7b in the inhibition of hepatic stellate cell activation by rSjP40
BACKGROUND: Hepatic stellate cells (HSCs) are one of the main cell types involved in liver fibrosis induced by many factors, including schistosomes. Previous studies in our lab have shown that recombinant P40 protein from Schistosoma japonicum (rSjP40) can inhibit HSC activation in vitro. Let-7b is...
Autores principales: | Sun, Xiaolei, Zhang, Li, Jiang, Yuting, Li, Aihong, Zhu, Dandan, Wu, Jiangrong, Duan, Yinong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221521/ https://www.ncbi.nlm.nih.gov/pubmed/34161325 http://dx.doi.org/10.1371/journal.pntd.0009472 |
Ejemplares similares
-
rSjP40 suppresses hepatic stellate cell activation by promoting microRNA‐155 expression and inhibiting STAT5 and FOXO3a expression
por: Zhu, Dandan, et al.
Publicado: (2018) -
rSjP40 Inhibited the Activity of Collagen Type I Promoter via Ets-1 in HSCs
por: Li, Jing, et al.
Publicado: (2021) -
rSjp40 inhibits activated hepatic stellate cells by promoting nuclear translocation of YB1 and inducing BMP-7/Smad1/5/8 pathway
por: Chen, Liuting, et al.
Publicado: (2019) -
Recombinant SjP40 protein enhances p27 promoter expression in hepatic stellate cells via an E2F1-dependent mechanism
por: Duan, Yinong, et al.
Publicado: (2017) -
Egg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells via SKP2/P27 signaling pathway
por: Xu, Tianhua, et al.
Publicado: (2017)