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The role of let-7b in the inhibition of hepatic stellate cell activation by rSjP40

BACKGROUND: Hepatic stellate cells (HSCs) are one of the main cell types involved in liver fibrosis induced by many factors, including schistosomes. Previous studies in our lab have shown that recombinant P40 protein from Schistosoma japonicum (rSjP40) can inhibit HSC activation in vitro. Let-7b is...

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Detalles Bibliográficos
Autores principales: Sun, Xiaolei, Zhang, Li, Jiang, Yuting, Li, Aihong, Zhu, Dandan, Wu, Jiangrong, Duan, Yinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221521/
https://www.ncbi.nlm.nih.gov/pubmed/34161325
http://dx.doi.org/10.1371/journal.pntd.0009472

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