Rejection of benign melanocytic nevi by nevus-resident CD4(+) T cells

Melanoma and melanocytic nevi harbor shared lineage-specific antigens and oncogenic mutations. Yet, the relationship between the immune system and melanocytic nevi is unclear. Using a patient-derived xenograft (PDX) model, we found that 81.8% of the transplanted nevi underwent spontaneous regression...

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Detalles Bibliográficos
Autores principales: Schiferle, Erik B., Cheon, Se Yun, Ham, Seokjin, Son, Heehwa G., Messerschmidt, Jonathan L., Lawrence, Donald P., Cohen, Justine V., Flaherty, Keith T., Moon, James J., Lian, Christine G., Sullivan, Ryan J., Demehri, Shadmehr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221625/
https://www.ncbi.nlm.nih.gov/pubmed/34162549
http://dx.doi.org/10.1126/sciadv.abg4498

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