A Leep1 into migration and macropinocytosis

Actin organization underpins conserved functions at the leading edge of cells. In this issue, Yang et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202010096) characterize Leep1 as a bi-functional regulator of migration and macropinocytosis through PIP(3) and the Scar/WAVE complex.

Detalles Bibliográficos
Autores principales: Koh, Yvette W.H., Stow, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221735/
https://www.ncbi.nlm.nih.gov/pubmed/34128957
http://dx.doi.org/10.1083/jcb.202105141
Descripción
Sumario:Actin organization underpins conserved functions at the leading edge of cells. In this issue, Yang et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202010096) characterize Leep1 as a bi-functional regulator of migration and macropinocytosis through PIP(3) and the Scar/WAVE complex.

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