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Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report

Obesity is closely linked to non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NASH), the latter now being the most common cause of cirrhosis in Western countries. Only a few cases have been described, such as the unexpected death after interrupted obesity surgery in a patient due...

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Autores principales: Käkelä, Pirjo, Rantanen, Tuomo, Paajanen, Hannu, Virtanen, Kirsi A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221815/
https://www.ncbi.nlm.nih.gov/pubmed/34178303
http://dx.doi.org/10.1093/jscr/rjab247
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author Käkelä, Pirjo
Rantanen, Tuomo
Paajanen, Hannu
Virtanen, Kirsi A
author_facet Käkelä, Pirjo
Rantanen, Tuomo
Paajanen, Hannu
Virtanen, Kirsi A
author_sort Käkelä, Pirjo
collection PubMed
description Obesity is closely linked to non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NASH), the latter now being the most common cause of cirrhosis in Western countries. Only a few cases have been described, such as the unexpected death after interrupted obesity surgery in a patient due to inaccurate preoperative imaging assessment. We describe a 53-year-old male patient with multiple comorbidities partly related to his obesity. A laparoscopic Roux-en-Y gastric bypass (LRYGB) was attempted. During anaesthesia, the patient had a cardiac arrhythmia and a short asystole. Intra-operative findings indicated a giant spleen and, unexpectedly, a cirrhotic liver. The LRYGB operation was interrupted. After 19 months, the patient died due to his severe comorbidities. Preoperative imaging missed the diagnosis of liver cirrhosis and related NASH. Since a challenging liver failure diagnosis cannot only rely on current imaging, we suggest that a liver biopsy is performed prior to LRYGB if preoperative imaging indicates cirrhotic liver.
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spelling pubmed-82218152021-06-24 Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report Käkelä, Pirjo Rantanen, Tuomo Paajanen, Hannu Virtanen, Kirsi A J Surg Case Rep Case Report Obesity is closely linked to non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NASH), the latter now being the most common cause of cirrhosis in Western countries. Only a few cases have been described, such as the unexpected death after interrupted obesity surgery in a patient due to inaccurate preoperative imaging assessment. We describe a 53-year-old male patient with multiple comorbidities partly related to his obesity. A laparoscopic Roux-en-Y gastric bypass (LRYGB) was attempted. During anaesthesia, the patient had a cardiac arrhythmia and a short asystole. Intra-operative findings indicated a giant spleen and, unexpectedly, a cirrhotic liver. The LRYGB operation was interrupted. After 19 months, the patient died due to his severe comorbidities. Preoperative imaging missed the diagnosis of liver cirrhosis and related NASH. Since a challenging liver failure diagnosis cannot only rely on current imaging, we suggest that a liver biopsy is performed prior to LRYGB if preoperative imaging indicates cirrhotic liver. Oxford University Press 2021-06-23 /pmc/articles/PMC8221815/ /pubmed/34178303 http://dx.doi.org/10.1093/jscr/rjab247 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2021. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Käkelä, Pirjo
Rantanen, Tuomo
Paajanen, Hannu
Virtanen, Kirsi A
Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report
title Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report
title_full Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report
title_fullStr Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report
title_full_unstemmed Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report
title_short Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report
title_sort fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221815/
https://www.ncbi.nlm.nih.gov/pubmed/34178303
http://dx.doi.org/10.1093/jscr/rjab247
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