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Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques

One of the key roles of an orthopedic surgeon treating metastatic bone disease (MBD) is fracture risk prediction. Current widely used impending fracture risk tools such as Mirels scoring lack specificity. Two newer methods of fracture risk prediction, CT-based structural rigidity analysis (CTRA) and...

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Autores principales: Kaupp, Shannon M., Mann, Kenneth A., Miller, Mark A., Damron, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221853/
https://www.ncbi.nlm.nih.gov/pubmed/34221514
http://dx.doi.org/10.1155/2021/5591715
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author Kaupp, Shannon M.
Mann, Kenneth A.
Miller, Mark A.
Damron, Timothy A.
author_facet Kaupp, Shannon M.
Mann, Kenneth A.
Miller, Mark A.
Damron, Timothy A.
author_sort Kaupp, Shannon M.
collection PubMed
description One of the key roles of an orthopedic surgeon treating metastatic bone disease (MBD) is fracture risk prediction. Current widely used impending fracture risk tools such as Mirels scoring lack specificity. Two newer methods of fracture risk prediction, CT-based structural rigidity analysis (CTRA) and finite element analysis (FEA), have each been shown to be more accurate than Mirels. This case series illustrates comparative Mirels, CTRA, and FEA for 8 femurs in 7 subjects. These cases were selected from a much larger data set to portray examples of true positives, true negatives, false positives, and false negatives as defined by CTRA relative to the fracture outcome. Case illustrations demonstrate comparative Mirels and FEA. This series illustrates the use, efficacy, and limitations of these tools. As all current tools have limitations, further work is needed in refining and developing fracture risk prediction.
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spelling pubmed-82218532021-07-02 Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques Kaupp, Shannon M. Mann, Kenneth A. Miller, Mark A. Damron, Timothy A. Adv Orthop Research Article One of the key roles of an orthopedic surgeon treating metastatic bone disease (MBD) is fracture risk prediction. Current widely used impending fracture risk tools such as Mirels scoring lack specificity. Two newer methods of fracture risk prediction, CT-based structural rigidity analysis (CTRA) and finite element analysis (FEA), have each been shown to be more accurate than Mirels. This case series illustrates comparative Mirels, CTRA, and FEA for 8 femurs in 7 subjects. These cases were selected from a much larger data set to portray examples of true positives, true negatives, false positives, and false negatives as defined by CTRA relative to the fracture outcome. Case illustrations demonstrate comparative Mirels and FEA. This series illustrates the use, efficacy, and limitations of these tools. As all current tools have limitations, further work is needed in refining and developing fracture risk prediction. Hindawi 2021-06-16 /pmc/articles/PMC8221853/ /pubmed/34221514 http://dx.doi.org/10.1155/2021/5591715 Text en Copyright © 2021 Shannon M. Kaupp et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kaupp, Shannon M.
Mann, Kenneth A.
Miller, Mark A.
Damron, Timothy A.
Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_full Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_fullStr Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_full_unstemmed Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_short Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_sort predicting fracture risk in patients with metastatic bone disease of the femur: a pictorial review using three different techniques
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221853/
https://www.ncbi.nlm.nih.gov/pubmed/34221514
http://dx.doi.org/10.1155/2021/5591715
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