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Enhanced H3K4 Trimethylation in TNF-α Promoter Gene Locus with Cell Apoptosis in the Ventral-Medial Striatum following Opioid Withdrawal of Neonatal Rat Offspring from Morphine-Addicted Mothers
Prenatal opioid exposure might disturb epigenetic programming in the brain of neonatal offspring with various consequences for gene expressions and behaviors. This study determined whether altered trimethylation of histone 3 at lysine 4 (H3K4me3) in the promoter of the tumor necrosis factor-α (tnf-α...
Autores principales: | Wu, Pei-Ling, Suen, Jau-Ling, Yang, Chun-Hwa, Kuo, Kuang-Che, Yang, Yu-Chen S. H., Yang, San-Nan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221879/ https://www.ncbi.nlm.nih.gov/pubmed/34220336 http://dx.doi.org/10.1155/2021/9828995 |
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