Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease

Despite the introduction of public health measures and spike protein-based vaccines to mitigate the COVID-19 pandemic, SARS-CoV-2 infections and deaths continue to have a global impact. Previously, we used a structural design approach to develop picomolar range miniproteins targeting the SARS-CoV-2...

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Detalles Bibliográficos
Autores principales: Case, James Brett, Chen, Rita E., Cao, Longxing, Ying, Baoling, Winkler, Emma S., Johnson, Max, Goreshnik, Inna, Pham, Minh N., Shrihari, Swathi, Kafai, Natasha M., Bailey, Adam L., Xie, Xuping, Shi, Pei-Yong, Ravichandran, Rashmi, Carter, Lauren, Stewart, Lance, Baker, David, Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221914/
https://www.ncbi.nlm.nih.gov/pubmed/34192518
http://dx.doi.org/10.1016/j.chom.2021.06.008

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