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Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism

Group 3 innate lymphoid cells (ILC3) have a prominent role in the maintenance of intestine mucosa homeostasis. The hypoxia-inducible factor (HIF) is an important modulator of immune cell activation and a key mechanism for cellular adaptation to oxygen deprivation. However, its role on ILC3 is not we...

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Detalles Bibliográficos
Autores principales: Fachi, J. L., Pral, L. P., dos Santos, J. A. C., Codo, A. C., de Oliveira, S., Felipe, J. S., Zambom, F. F. F., Câmara, N. O. S., Vieira, P. M. M. M., Colonna, M., Vinolo, M. A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221997/
https://www.ncbi.nlm.nih.gov/pubmed/33446906
http://dx.doi.org/10.1038/s41385-020-00371-6