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Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism
Group 3 innate lymphoid cells (ILC3) have a prominent role in the maintenance of intestine mucosa homeostasis. The hypoxia-inducible factor (HIF) is an important modulator of immune cell activation and a key mechanism for cellular adaptation to oxygen deprivation. However, its role on ILC3 is not we...
Autores principales: | Fachi, J. L., Pral, L. P., dos Santos, J. A. C., Codo, A. C., de Oliveira, S., Felipe, J. S., Zambom, F. F. F., Câmara, N. O. S., Vieira, P. M. M. M., Colonna, M., Vinolo, M. A. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221997/ https://www.ncbi.nlm.nih.gov/pubmed/33446906 http://dx.doi.org/10.1038/s41385-020-00371-6 |
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