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Analysis of COVID-19 using a modified SLIR model with nonlinear incidence
Infectious diseases kill millions of people each year, and they are the major public health problem in the world. This paper presents a modified Susceptible-Latent-Infected-Removed (SLIR) compartmental model of disease transmission with nonlinear incidence. We have obtained a threshold value of basi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222049/ https://www.ncbi.nlm.nih.gov/pubmed/34183903 http://dx.doi.org/10.1016/j.rinp.2021.104478 |
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author | Kuddus, Md Abdul Rahman, Azizur |
author_facet | Kuddus, Md Abdul Rahman, Azizur |
author_sort | Kuddus, Md Abdul |
collection | PubMed |
description | Infectious diseases kill millions of people each year, and they are the major public health problem in the world. This paper presents a modified Susceptible-Latent-Infected-Removed (SLIR) compartmental model of disease transmission with nonlinear incidence. We have obtained a threshold value of basic reproduction number [Formula: see text] and shown that only a disease-free equilibrium exists when [Formula: see text] and endemic equilibrium when [Formula: see text]. With the help of the Lyapunov-LaSalle Invariance Principle, we have shown that disease-free equilibrium and endemic equilibrium are both globally asymptotically stable. The study has also provided the model calibration to estimate parameters with month wise coronavirus (COVID-19) data, i.e. reported cases by worldometer from March 2020 to May 2021 and provides prediction until December 2021 in China. The Partial Rank Correlation Coefficient (PRCC) method was used to investigate how the model parameters’ variation impact the model outcomes. We observed that the most important parameter is transmission rate which had the most significant impact on COVID-19 cases. We also discuss the epidemiology of COVID-19 cases and several control policies and make recommendations for controlling this disease in China. |
format | Online Article Text |
id | pubmed-8222049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82220492021-06-24 Analysis of COVID-19 using a modified SLIR model with nonlinear incidence Kuddus, Md Abdul Rahman, Azizur Results Phys Article Infectious diseases kill millions of people each year, and they are the major public health problem in the world. This paper presents a modified Susceptible-Latent-Infected-Removed (SLIR) compartmental model of disease transmission with nonlinear incidence. We have obtained a threshold value of basic reproduction number [Formula: see text] and shown that only a disease-free equilibrium exists when [Formula: see text] and endemic equilibrium when [Formula: see text]. With the help of the Lyapunov-LaSalle Invariance Principle, we have shown that disease-free equilibrium and endemic equilibrium are both globally asymptotically stable. The study has also provided the model calibration to estimate parameters with month wise coronavirus (COVID-19) data, i.e. reported cases by worldometer from March 2020 to May 2021 and provides prediction until December 2021 in China. The Partial Rank Correlation Coefficient (PRCC) method was used to investigate how the model parameters’ variation impact the model outcomes. We observed that the most important parameter is transmission rate which had the most significant impact on COVID-19 cases. We also discuss the epidemiology of COVID-19 cases and several control policies and make recommendations for controlling this disease in China. Published by Elsevier B.V. 2021-08 2021-06-21 /pmc/articles/PMC8222049/ /pubmed/34183903 http://dx.doi.org/10.1016/j.rinp.2021.104478 Text en © 2021 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Kuddus, Md Abdul Rahman, Azizur Analysis of COVID-19 using a modified SLIR model with nonlinear incidence |
title | Analysis of COVID-19 using a modified SLIR model with nonlinear incidence |
title_full | Analysis of COVID-19 using a modified SLIR model with nonlinear incidence |
title_fullStr | Analysis of COVID-19 using a modified SLIR model with nonlinear incidence |
title_full_unstemmed | Analysis of COVID-19 using a modified SLIR model with nonlinear incidence |
title_short | Analysis of COVID-19 using a modified SLIR model with nonlinear incidence |
title_sort | analysis of covid-19 using a modified slir model with nonlinear incidence |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222049/ https://www.ncbi.nlm.nih.gov/pubmed/34183903 http://dx.doi.org/10.1016/j.rinp.2021.104478 |
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