Vitamin D Deficiency-induced Osteomalacia in a Patient with Anorexia Nervosa

A 48-year-old woman with a 9-year-history of anorexia nervosa (AN) was admitted complaining of generalized bone pain. Blood tests showed hypocalcemia and hyperphosphatasemia, and a radiological survey revealed multiple rib fractures, suggesting complication with osteomalacia. Two years earlier, she...

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Autores principales: Koda, Ryo, Miyazaki, Satoru, Iino, Noriaki, Sato, Yo, Hirano, Kenichiro, Sunami, Eiji, Kosugi, Shinichi, Kanefuji, Tsutomu, Ogose, Akira, Narita, Ichiei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222131/
https://www.ncbi.nlm.nih.gov/pubmed/33390486
http://dx.doi.org/10.2169/internalmedicine.5911-20
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author Koda, Ryo
Miyazaki, Satoru
Iino, Noriaki
Sato, Yo
Hirano, Kenichiro
Sunami, Eiji
Kosugi, Shinichi
Kanefuji, Tsutomu
Ogose, Akira
Narita, Ichiei
author_facet Koda, Ryo
Miyazaki, Satoru
Iino, Noriaki
Sato, Yo
Hirano, Kenichiro
Sunami, Eiji
Kosugi, Shinichi
Kanefuji, Tsutomu
Ogose, Akira
Narita, Ichiei
author_sort Koda, Ryo
collection PubMed
description A 48-year-old woman with a 9-year-history of anorexia nervosa (AN) was admitted complaining of generalized bone pain. Blood tests showed hypocalcemia and hyperphosphatasemia, and a radiological survey revealed multiple rib fractures, suggesting complication with osteomalacia. Two years earlier, she had undergone subtotal colectomy for colon cancer. Her serum 25-hydroxy vitamin D concentration was below the detectable level. In addition to a poor nutritional intake and insufficient sun exposure, malabsorption of fat-soluble substances in the intestine and phosphate loss from the kidneys might have contributed to the development of her osteomalacia.
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spelling pubmed-82221312021-06-27 Vitamin D Deficiency-induced Osteomalacia in a Patient with Anorexia Nervosa Koda, Ryo Miyazaki, Satoru Iino, Noriaki Sato, Yo Hirano, Kenichiro Sunami, Eiji Kosugi, Shinichi Kanefuji, Tsutomu Ogose, Akira Narita, Ichiei Intern Med Case Report A 48-year-old woman with a 9-year-history of anorexia nervosa (AN) was admitted complaining of generalized bone pain. Blood tests showed hypocalcemia and hyperphosphatasemia, and a radiological survey revealed multiple rib fractures, suggesting complication with osteomalacia. Two years earlier, she had undergone subtotal colectomy for colon cancer. Her serum 25-hydroxy vitamin D concentration was below the detectable level. In addition to a poor nutritional intake and insufficient sun exposure, malabsorption of fat-soluble substances in the intestine and phosphate loss from the kidneys might have contributed to the development of her osteomalacia. The Japanese Society of Internal Medicine 2020-12-29 2021-06-01 /pmc/articles/PMC8222131/ /pubmed/33390486 http://dx.doi.org/10.2169/internalmedicine.5911-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Koda, Ryo
Miyazaki, Satoru
Iino, Noriaki
Sato, Yo
Hirano, Kenichiro
Sunami, Eiji
Kosugi, Shinichi
Kanefuji, Tsutomu
Ogose, Akira
Narita, Ichiei
Vitamin D Deficiency-induced Osteomalacia in a Patient with Anorexia Nervosa
title Vitamin D Deficiency-induced Osteomalacia in a Patient with Anorexia Nervosa
title_full Vitamin D Deficiency-induced Osteomalacia in a Patient with Anorexia Nervosa
title_fullStr Vitamin D Deficiency-induced Osteomalacia in a Patient with Anorexia Nervosa
title_full_unstemmed Vitamin D Deficiency-induced Osteomalacia in a Patient with Anorexia Nervosa
title_short Vitamin D Deficiency-induced Osteomalacia in a Patient with Anorexia Nervosa
title_sort vitamin d deficiency-induced osteomalacia in a patient with anorexia nervosa
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222131/
https://www.ncbi.nlm.nih.gov/pubmed/33390486
http://dx.doi.org/10.2169/internalmedicine.5911-20
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