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Electro-steric opening of the clc-2 chloride channel gate

The widely expressed two-pore homodimeric inward rectifier CLC-2 chloride channel regulates transepithelial chloride transport, extracellular chloride homeostasis, and neuronal excitability. Each pore is independently gated at hyperpolarized voltages by a conserved pore glutamate. Presumably, exitin...

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Detalles Bibliográficos
Autores principales:	De Jesús-Pérez, José J., Méndez-Maldonado, G. Arlette, López-Romero, Ana E., Esparza-Jasso, David, González-Hernández, Irma L., De la Rosa, Víctor, Gastélum-Garibaldi, Roberto, Sánchez-Rodríguez, Jorge E., Arreola, Jorge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222222/ https://www.ncbi.nlm.nih.gov/pubmed/34162897 http://dx.doi.org/10.1038/s41598-021-92247-3

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