Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals

The COVID-19 pandemic has revealed a range of disease phenotypes in infected patients with asymptomatic, mild, or severe clinical outcomes, but the mechanisms that determine such variable outcomes remain unresolved. In this study, we identified immunodominant CD8 T-cell epitopes in the spike antigen...

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Detalles Bibliográficos
Autores principales: Mahajan, Swapnil, Kode, Vasumathi, Bhojak, Keshav, Karunakaran, Coral, Lee, Kayla, Manoharan, Malini, Ramesh, Athulya, HV, Sudheendra, Srivastava, Ankita, Sathian, Rekha, Khan, Tahira, Kumar, Prasanna, Gupta, Ravi, Chakraborty, Papia, Chaudhuri, Amitabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222233/
https://www.ncbi.nlm.nih.gov/pubmed/34162945
http://dx.doi.org/10.1038/s41598-021-92521-4

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