Irreversible electroporation augments checkpoint immunotherapy in prostate cancer and promotes tumor antigen-specific tissue-resident memory CD8+ T cells

Memory CD8+ T cells populate non-lymphoid tissues (NLTs) following pathogen infection, but little is known about the establishment of endogenous tumor-specific tissue-resident memory T cells (T(RM)) during cancer immunotherapy. Using a transplantable mouse model of prostate carcinoma, here we report...

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Detalles Bibliográficos
Autores principales: Burbach, Brandon J., O’Flanagan, Stephen D., Shao, Qi, Young, Katharine M., Slaughter, Joseph R., Rollins, Meagan R., Street, Tami Jo L., Granger, Victoria E., Beura, Lalit. K., Azarin, Samira M., Ramadhyani, Satish, Forsyth, Bruce R., Bischof, John C., Shimizu, Yoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222297/
https://www.ncbi.nlm.nih.gov/pubmed/34162858
http://dx.doi.org/10.1038/s41467-021-24132-6

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