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Reduced dose of PTCy followed by adjuvant α-galactosylceramide enhances GVL effect without sacrificing GVHD suppression
Posttransplantation cyclophosphamide (PTCy) has become a popular option for haploidentical hematopoietic stem cell transplantation (HSCT). However, personalized methods to adjust immune intensity after PTCy for each patient’s condition have not been well studied. Here, we investigated the effects of...
Autores principales: | Nakamura, Makoto, Meguri, Yusuke, Ikegawa, Shuntaro, Kondo, Takumi, Sumii, Yuichi, Fukumi, Takuya, Iwamoto, Miki, Sando, Yasuhisa, Sugiura, Hiroyuki, Asada, Noboru, Ennishi, Daisuke, Tomida, Shuta, Fukuda-Kawaguchi, Emi, Ishii, Yasuyuki, Maeda, Yoshinobu, Matsuoka, Ken-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222309/ https://www.ncbi.nlm.nih.gov/pubmed/34162921 http://dx.doi.org/10.1038/s41598-021-92526-z |
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