TXNIP, a novel key factor to cause Schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression

Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes mellitus (DM) and the dysfunction of Schwann cells plays an important role in the pathogenesis of DPN. Thioredoxin-interacting protein (TXNIP) is known as an inhibitor of thioredoxin and associated with oxidative stress...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang, Zhao, Song, Yuan, Qingqing, Zhu, Lin, Li, Fan, Wang, Hui, Kong, Dezhi, Hao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222353/
https://www.ncbi.nlm.nih.gov/pubmed/34162834
http://dx.doi.org/10.1038/s41419-021-03930-2

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