A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial

Precision oncology is currently based on pairing molecularly targeted agents (MTA) to predefined single driver genes or biomarkers. Each tumor harbors a combination of a large number of potential genetic alterations of multiple driver genes in a complex system that limits the potential of this appro...

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Detalles Bibliográficos
Autores principales: Petak, Istvan, Kamal, Maud, Dirner, Anna, Bieche, Ivan, Doczi, Robert, Mariani, Odette, Filotas, Peter, Salomon, Anne, Vodicska, Barbara, Servois, Vincent, Varkondi, Edit, Gentien, David, Tihanyi, Dora, Tresca, Patricia, Lakatos, Dora, Servant, Nicolas, Deri, Julia, du Rusquec, Pauline, Hegedus, Csilla, Bello Roufai, Diana, Schwab, Richard, Dupain, Celia, Valyi-Nagy, Istvan T., Le Tourneau, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222375/
https://www.ncbi.nlm.nih.gov/pubmed/34162980
http://dx.doi.org/10.1038/s41698-021-00191-2

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