Rapid proliferation due to better metabolic adaptation results in full virulence of a filament-deficient Candida albicans strain

The ability of the fungal pathogen Candida albicans to undergo a yeast-to-hypha transition is believed to be a key virulence factor, as filaments mediate tissue damage. Here, we show that virulence is not necessarily reduced in filament-deficient strains, and the results depend on the infection mode...

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Detalles Bibliográficos
Autores principales: Dunker, Christine, Polke, Melanie, Schulze-Richter, Bianca, Schubert, Katja, Rudolphi, Sven, Gressler, A. Elisabeth, Pawlik, Tony, Prada Salcedo, Juan P., Niemiec, M. Joanna, Slesiona-Künzel, Silvia, Swidergall, Marc, Martin, Ronny, Dandekar, Thomas, Jacobsen, Ilse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222383/
https://www.ncbi.nlm.nih.gov/pubmed/34162849
http://dx.doi.org/10.1038/s41467-021-24095-8

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