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Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus
The decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Lifestyle interventions can improve brain function during aging, but their influence on age-related epigenetic changes is unknown. Using genome-wide DNA methylation sequencing, we here show t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222384/ https://www.ncbi.nlm.nih.gov/pubmed/34162876 http://dx.doi.org/10.1038/s41467-021-23993-1 |