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Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus

The decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Lifestyle interventions can improve brain function during aging, but their influence on age-related epigenetic changes is unknown. Using genome-wide DNA methylation sequencing, we here show t...

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Detalles Bibliográficos
Autores principales:	Zocher, Sara, Overall, Rupert W., Lesche, Mathias, Dahl, Andreas, Kempermann, Gerd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222384/ https://www.ncbi.nlm.nih.gov/pubmed/34162876 http://dx.doi.org/10.1038/s41467-021-23993-1

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