Generation of two induced pluripotent stem cell (iPSC) lines from an ALS patient with simultaneous mutations in KIF5A and MATR3 genes

Fibroblasts from an amyotrophic lateral sclerosis patient with simultaneous mutations in the MATR3 gene and KIF5A gene were isolated and reprogrammed into induced pluripotent stem cells via a non-integrating Sendai viral vector. The generated iPSC clones demonstrated normal karyotype, expression of...

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Detalles Bibliográficos
Autores principales: Medina, David X., Boehringer, Ashley, Dominick, Marissa, Lorenzini, Ileana, Saez-Atienzar, Sara, Pioro, Erik P., Sattler, Rita, Traynor, Bryan, Bowser, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222416/
https://www.ncbi.nlm.nih.gov/pubmed/33388707
http://dx.doi.org/10.1016/j.scr.2020.102141

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