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The Anti-Non-Small Cell Lung Cancer Cell Activity by a mTOR Kinase Inhibitor PQR620

In non-small-cell lung carcinoma (NSCLC), aberrant activation of mammalian target of rapamycin (mTOR) contributes to tumorigenesis and cancer progression. PQR620 is a novel and highly-potent mTOR kinase inhibitor. We here tested its potential activity in NSCLC cells. In primary human NSCLC cells and...

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Detalles Bibliográficos
Autores principales:	Zha, Jian-hua, Xia, Ying-chen, Ye, Chun-lin, Hu, Zhi, Zhang, Qin, Xiao, Han, Yu, Ben-tong, Xu, Wei-hua, Xu, Guo-qiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222575/ https://www.ncbi.nlm.nih.gov/pubmed/34178653 http://dx.doi.org/10.3389/fonc.2021.669518

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