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A Genome-Wide Association Study and Polygenic Risk Score Analysis of Posttraumatic Stress Disorder and Metabolic Syndrome in a South African Population

Posttraumatic stress disorder (PTSD) is a trauma-related disorder that frequently co-occurs with metabolic syndrome (MetS). MetS is characterized by obesity, dyslipidemia, and insulin resistance. To provide insight into these co-morbidities, we performed a genome-wide association study (GWAS) meta-a...

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Detalles Bibliográficos
Autores principales: Swart, Patricia C., van den Heuvel, Leigh L., Lewis, Cathryn M., Seedat, Soraya, Hemmings, Sian M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222611/
https://www.ncbi.nlm.nih.gov/pubmed/34177453
http://dx.doi.org/10.3389/fnins.2021.677800