The Yin and Yang of Type 1 Regulatory T Cells: From Discovery to Clinical Application

Regulatory T cells are essential players of peripheral tolerance and suppression of inflammatory immune responses. Type 1 regulatory T (Tr1) cells are FoxP3(-) regulatory T cells induced in the periphery under tolerogenic conditions. Tr1 cells are identified as LAG3(+)CD49b(+) mature CD4(+) T cells...

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Detalles Bibliográficos
Autores principales: Sayitoglu, Ece Canan, Freeborn, Robert Arthur, Roncarolo, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222711/
https://www.ncbi.nlm.nih.gov/pubmed/34177953
http://dx.doi.org/10.3389/fimmu.2021.693105

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