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MCM4 Is a Novel Biomarker Associated With Genomic Instability, BRCAness Phenotype, and Therapeutic Potentials in Soft-Tissue Sarcoma

Soft-tissue sarcoma (STS) is represented by a heterogeneous group of rare malignancies with various molecular oncogenesis. Therapies targeting DNA repair pathways in STS have achieved minimal progress, potentially due to the lack of molecular biomarker(s) beyond the histology subtype. In this report...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Bao, Qiyuan, Xu, Yiqi, Fu, Yucheng, Jin, Zhijian, Wang, Jun, Zhang, Weibin, Shen, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222794/
https://www.ncbi.nlm.nih.gov/pubmed/34178990
http://dx.doi.org/10.3389/fcell.2021.666376