Cargando…
Tripterygium glycoside suppresses epithelial-to-mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway
Tripterygium glycoside (TG) is a traditional Chinese medicine extract with immunosuppressive, anti-inflammatory and anti-renal fibrosis effects. Epithelial-mesenchymal transition (EMT) and cell apoptosis are considered to be the major cause of podocyte injury in diabetic kidney disease (DKD). Howeve...
Autores principales: | Tao, Mei, Zheng, Danna, Liang, Xudong, Wu, Diandian, Hu, Kang, Jin, Juan, He, Qiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222798/ https://www.ncbi.nlm.nih.gov/pubmed/34165172 http://dx.doi.org/10.3892/mmr.2021.12231 |
Ejemplares similares
-
Tripterygium glycoside protects against puromycin amino nucleoside-induced podocyte injury by upregulating autophagy
por: Gong, Jianguang, et al.
Publicado: (2018) -
Revisiting mTOR and Epithelial–Mesenchymal Transition
por: Herrerias, Mariana M., et al.
Publicado: (2020) -
RAMS11 promotes CRC through mTOR-dependent inhibition of autophagy, suppression of apoptosis, and promotion of epithelial-mesenchymal transition
por: Islam Khan, Md Zahirul, et al.
Publicado: (2021) -
Wells Syndrome Successfully Treated with Tripterygium Glycosides
por: Lu, Jiejie, et al.
Publicado: (2021) -
Clinical Practice Guideline for Tripterygium Glycosides/Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis
por: Lin, Na, et al.
Publicado: (2021)