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Thermodynamic Analysis for Binding of 4-O-β-tri-N-acetylchitotriosyl Moranoline, a Transition State Analogue Inhibitor for Hen Egg White Lysozyme

4-O-β-tri-N-acetylchitotriosyl moranoline (GN(3)M) is a transition-state analogue for hen egg white lysozyme (HEWL) and identified as the most potent inhibitor till date. Isothermal titration calorimetry experiments provided the thermodynamic parameters for binding of GN(3)M to HEWL and revealed tha...

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Detalles Bibliográficos
Autores principales:	Ogata, Makoto, Fukamizo, Tamo, Ohnuma, Takayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222817/ https://www.ncbi.nlm.nih.gov/pubmed/34179076 http://dx.doi.org/10.3389/fmolb.2021.654706

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