Cargando…

α-synuclein pathogenesis in hiPSC models of Parkinson’s disease

α-synuclein is an increasingly prominent player in the pathology of a variety of neurodegenerative conditions. Parkinson’s disease (PD) is a neurodegenerative disorder that affects mainly the dopaminergic (DA) neurons in the substantia nigra of the brain. Typical of PD pathology is the finding of pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baena-Montes, Jara M., Avazzadeh, Sahar, Quinlan, Leo R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222967/ https://www.ncbi.nlm.nih.gov/pubmed/34239711 http://dx.doi.org/10.1042/NS20210021

Ejemplares similares

hiPSC-Based Model of Prenatal Exposure to Cannabinoids: Effect on Neuronal Differentiation
por: Miranda, Cláudia C., et al.
Publicado: (2020)

All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors
por: Puppo, Francesca, et al.
Publicado: (2021)

hiPSC-Derived Cells as Models for Drug Discovery
por: Ofir, Rivka
Publicado: (2021)

A mathematical model of hiPSC cardiomyocytes electromechanics
por: Forouzandehmehr, Mohamadamin, et al.
Publicado: (2021)

Modelling Parkinson’s Disease: iPSCs towards Better Understanding of Human Pathology
por: Avazzadeh, Sahar, et al.
Publicado: (2021)

Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases
por: Trudler, Dorit, et al.
Publicado: (2021)

Reliability of human retina organoid generation from hiPSC-derived neuroepithelial cysts
por: Carido, Madalena, et al.
Publicado: (2023)

New considerations for hiPSC-based models of neuropsychiatric disorders
por: Hoffman, Gabriel E., et al.
Publicado: (2018)

Editing the genome of hiPSC with CRISPR/Cas9: disease models
por: Bassett, Andrew R.
Publicado: (2017)

hiPSC-Derived Cardiac Tissue for Disease Modeling and Drug Discovery
por: Li, Junjun, et al.
Publicado: (2020)

Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls
por: Ghatak, Swagata, et al.
Publicado: (2019)

Characterizing the secretome of licensed hiPSC-derived MSCs
por: Ramos, Yolande F. M., et al.
Publicado: (2022)

Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs
por: Metzler, Eric, et al.
Publicado: (2022)

Divergent Levels of Marker Chromosomes in an hiPSC-Based Model of Psychosis
por: TCW, Julia, et al.
Publicado: (2017)

An in silico hiPSC-Derived Cardiomyocyte Model Built With Genetic Algorithm
por: Akwaboah, Akwasi D., et al.
Publicado: (2021)

hiPSC-Derived Cells as Models for Drug Discovery 2.0
por: Ofir, Rivka
Publicado: (2023)

Reprogramming of HUVECs into Induced Pluripotent Stem Cells (HiPSCs), Generation and Characterization of HiPSC-Derived Neurons and Astrocytes
por: Haile, Yohannes, et al.
Publicado: (2015)

Comparison and Optimization of hiPSC Forebrain Cortical Differentiation Protocols
por: Muratore, Christina R., et al.
Publicado: (2014)

The Effect of Uncoated SPIONs on hiPSC-Differentiated Endothelial Cells
por: Salingova, Barbara, et al.
Publicado: (2019)

Considerations in hiPSC-derived cartilage for articular cartilage repair
por: Yamashita, Akihiro, et al.
Publicado: (2018)

Differentiation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons in Mouse Hippocampal Slice Cultures
por: Hiragi, Toshimitsu, et al.
Publicado: (2017)

Modeling Movement Disorders via Generation of hiPSC-Derived Motor Neurons
por: Akter, Masuma, et al.
Publicado: (2022)

Engineering hiPSC-CM and hiPSC-EC laden 3D nanofibrous splenic hydrogel for improving cardiac function through revascularization and remuscularization in infarcted heart
por: Guan, Ge, et al.
Publicado: (2021)

Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells
por: Francistiová, Linda, et al.
Publicado: (2022)

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
por: Brennand, K, et al.
Publicado: (2015)

Practical adoption of state-of-the-art hiPSC-cardiomyocyte differentiation techniques
por: Rupert, Cassady E., et al.
Publicado: (2020)

Protocol for Tri-culture of hiPSC-Derived Neurons, Astrocytes, and Microglia
por: Ryan, Sean K., et al.
Publicado: (2020)

Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids
por: Ramovs, Veronika, et al.
Publicado: (2022)

Vascularized hiPSC-derived 3D cardiac microtissue on chip
por: Arslan, Ulgu, et al.
Publicado: (2023)

Vascularized hiPSC-derived 3D cardiac microtissue on chip
por: Arslan, Ulgu, et al.
Publicado: (2023)

The role of the endolysosomal pathway in α-synuclein pathogenesis in Parkinson’s disease
por: Smith, Jessica K., et al.
Publicado: (2023)

Inhibition of STEP(61) ameliorates deficits in mouse and hiPSC-based schizophrenia models
por: Xu, J, et al.
Publicado: (2018)

NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models
por: Ghatak, Swagata, et al.
Publicado: (2021)

Perspectives on hiPSC-Derived Muscle Cells as Drug Discovery Models for Muscular Dystrophies
por: Abati, Elena, et al.
Publicado: (2021)

A village in a dish model system for population-scale hiPSC studies
por: Neavin, Drew R., et al.
Publicado: (2023)

The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening
por: Gonzalez, David M., et al.
Publicado: (2017)

Modeling Cardiovascular Diseases with hiPSC-Derived Cardiomyocytes in 2D and 3D Cultures
por: Sacchetto, Claudia, et al.
Publicado: (2020)

hiPSC-based models to decipher the contribution of human astrocytes to Alzheimer’s disease and potential therapeutics
por: TCW, Julia, et al.
Publicado: (2023)

Contractile Work Contributes to Maturation of Energy Metabolism in hiPSC-Derived Cardiomyocytes
por: Ulmer, Bärbel M., et al.
Publicado: (2018)

Microscopy-based cellular contractility assay for adult, neonatal, and hiPSC cardiomyocytes
por: Scalzo, Sérgio, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_87to2g2c8ekpqbajsn86ekjpps