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Effect of the protease plasmin on C. elegans hyperactive DEG/ENaC channels MEC-4(d) and UNC-8(d)
C. elegans MEC-4 and UNC-8 belong to the DEG/ENaC family of voltage-independent Na(+) channels and have been implicated in mechanosensation and synaptic remodeling. MEC-4 and UNC-8 hyperactive mutants, designated (d) mutants, conduct enhanced currents and cause cell death due to uncontrolled influx...
Autores principales: | Johnson, Christina K., Miller, David D., Bianchi, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Caltech Library
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223032/ https://www.ncbi.nlm.nih.gov/pubmed/34189421 http://dx.doi.org/10.17912/micropub.biology.000412 |
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