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ACE2 interaction with cytoplasmic PDZ protein enhances SARS-CoV-2 invasion

SARS-CoV-2 is responsible for the global COVID-19 pandemic. Angiotensin converting enzyme 2 (ACE2) is the membrane-delimited receptor for SARS-CoV-2. Lung, intestine, and kidney, major sites of viral infection, express ACE2 that harbors an intracellular, carboxy-terminal PDZ-recognition motif. These...

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Detalles Bibliográficos
Autores principales:	Zhang, Qiangmin, Gefter, Julia, Sneddon, W. Bruce, Mamonova, Tatyana, Friedman, Peter A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223119/ https://www.ncbi.nlm.nih.gov/pubmed/34189428 http://dx.doi.org/10.1016/j.isci.2021.102770

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