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Divanillyl sulfone suppresses NLRP3 inflammasome activation via inducing mitophagy to ameliorate chronic neuropathic pain in mice
BACKGROUND: Chronic neuropathic pain is a frequent sequel to peripheral nerve injury and maladaptive nervous system function. Divanillyl sulfone (DS), a novel structural derivative of 4,4′-dihydroxydibenzyl sulfoxide from a traditional Chinese medicine Gastrodia elata with anti-nociceptive effects,...
Autores principales: | Shao, Shuai, Xu, Cheng-Bo, Chen, Cheng-Juan, Shi, Gao-Na, Guo, Qing-Lan, Zhou, Yu, Wei, Ya-Zi, Wu, Lei, Shi, Jian-Gong, Zhang, Tian-Tai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223331/ https://www.ncbi.nlm.nih.gov/pubmed/34162415 http://dx.doi.org/10.1186/s12974-021-02178-z |
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