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Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up
OBJECTIVES: This study was performed to evaluate the efficacy of microwave ablation (MWA) eustachian tuboplasty for the treatment of patients with retracted tympanic membrane (TM) due to eustachian tube dysfunction (ETD). METHODS: This was a prospective study of 20 patients with ETD (middle ear atel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223355/ https://www.ncbi.nlm.nih.gov/pubmed/34167591 http://dx.doi.org/10.1186/s40463-021-00520-2 |
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author | Lou, Zhengcai Lou, Zihan Sun, Junzhi Chen, Zhengnong Yin, Shankai |
author_facet | Lou, Zhengcai Lou, Zihan Sun, Junzhi Chen, Zhengnong Yin, Shankai |
author_sort | Lou, Zhengcai |
collection | PubMed |
description | OBJECTIVES: This study was performed to evaluate the efficacy of microwave ablation (MWA) eustachian tuboplasty for the treatment of patients with retracted tympanic membrane (TM) due to eustachian tube dysfunction (ETD). METHODS: This was a prospective study of 20 patients with ETD (middle ear atelectasis) who underwent MWA eustachian tuboplasty. Outcomes included the ability to perform a Valsalva maneuver, audiometry results, tympanometry results, ETD Questionnaire (ETDQ-7) score, and TM status. RESULTS: Eighteen patients (18 ears) were included in this study. There were statistically and clinically significant improvements in the mean ETDQ-7 score at 6 months postoperatively (change in mean score of 16.7 ± 3.6, P < 0.001) and at 30 months postoperatively (change in mean score of 18.9 ± 2.9, P < 0.001). Type A tympanogram was obtained in 27.8% of patients (5/18) at 6 months postoperatively, and in 77.7% at 30 months postoperatively. A Valsalva maneuver was possible in 72.2% of patients at 6 months postoperatively and in 88.9% of patients at 30 months postoperatively. In addition, the ears of 13 patients (72.2%) showed both normal tympanograms and TM at 30 months postoperatively. Interestingly, 38.5% of patients (5/13) exhibited complete sclerosis of the pars tensa. None of the patients experienced severe MWA-related complications during follow-up. CONCLUSIONS: MWA eustachian tuboplasty is a feasible alternative to conventional tuboplasty, and can improve subjective and objective outcomes in patients with ETD for up to 30 months following treatment. In addition, this study showed that the extent of sclerotic plaque increased over time, whereas the extents of atrophy and tensa retraction decreased following tuboplasty in most patients. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-8223355 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-82233552021-06-24 Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up Lou, Zhengcai Lou, Zihan Sun, Junzhi Chen, Zhengnong Yin, Shankai J Otolaryngol Head Neck Surg Original Research Article OBJECTIVES: This study was performed to evaluate the efficacy of microwave ablation (MWA) eustachian tuboplasty for the treatment of patients with retracted tympanic membrane (TM) due to eustachian tube dysfunction (ETD). METHODS: This was a prospective study of 20 patients with ETD (middle ear atelectasis) who underwent MWA eustachian tuboplasty. Outcomes included the ability to perform a Valsalva maneuver, audiometry results, tympanometry results, ETD Questionnaire (ETDQ-7) score, and TM status. RESULTS: Eighteen patients (18 ears) were included in this study. There were statistically and clinically significant improvements in the mean ETDQ-7 score at 6 months postoperatively (change in mean score of 16.7 ± 3.6, P < 0.001) and at 30 months postoperatively (change in mean score of 18.9 ± 2.9, P < 0.001). Type A tympanogram was obtained in 27.8% of patients (5/18) at 6 months postoperatively, and in 77.7% at 30 months postoperatively. A Valsalva maneuver was possible in 72.2% of patients at 6 months postoperatively and in 88.9% of patients at 30 months postoperatively. In addition, the ears of 13 patients (72.2%) showed both normal tympanograms and TM at 30 months postoperatively. Interestingly, 38.5% of patients (5/13) exhibited complete sclerosis of the pars tensa. None of the patients experienced severe MWA-related complications during follow-up. CONCLUSIONS: MWA eustachian tuboplasty is a feasible alternative to conventional tuboplasty, and can improve subjective and objective outcomes in patients with ETD for up to 30 months following treatment. In addition, this study showed that the extent of sclerotic plaque increased over time, whereas the extents of atrophy and tensa retraction decreased following tuboplasty in most patients. GRAPHICAL ABSTRACT: [Image: see text] BioMed Central 2021-06-24 /pmc/articles/PMC8223355/ /pubmed/34167591 http://dx.doi.org/10.1186/s40463-021-00520-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Original Research Article Lou, Zhengcai Lou, Zihan Sun, Junzhi Chen, Zhengnong Yin, Shankai Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up |
title | Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up |
title_full | Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up |
title_fullStr | Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up |
title_full_unstemmed | Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up |
title_short | Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up |
title_sort | microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223355/ https://www.ncbi.nlm.nih.gov/pubmed/34167591 http://dx.doi.org/10.1186/s40463-021-00520-2 |
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