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Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up

OBJECTIVES: This study was performed to evaluate the efficacy of microwave ablation (MWA) eustachian tuboplasty for the treatment of patients with retracted tympanic membrane (TM) due to eustachian tube dysfunction (ETD). METHODS: This was a prospective study of 20 patients with ETD (middle ear atel...

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Autores principales: Lou, Zhengcai, Lou, Zihan, Sun, Junzhi, Chen, Zhengnong, Yin, Shankai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223355/
https://www.ncbi.nlm.nih.gov/pubmed/34167591
http://dx.doi.org/10.1186/s40463-021-00520-2
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author Lou, Zhengcai
Lou, Zihan
Sun, Junzhi
Chen, Zhengnong
Yin, Shankai
author_facet Lou, Zhengcai
Lou, Zihan
Sun, Junzhi
Chen, Zhengnong
Yin, Shankai
author_sort Lou, Zhengcai
collection PubMed
description OBJECTIVES: This study was performed to evaluate the efficacy of microwave ablation (MWA) eustachian tuboplasty for the treatment of patients with retracted tympanic membrane (TM) due to eustachian tube dysfunction (ETD). METHODS: This was a prospective study of 20 patients with ETD (middle ear atelectasis) who underwent MWA eustachian tuboplasty. Outcomes included the ability to perform a Valsalva maneuver, audiometry results, tympanometry results, ETD Questionnaire (ETDQ-7) score, and TM status. RESULTS: Eighteen patients (18 ears) were included in this study. There were statistically and clinically significant improvements in the mean ETDQ-7 score at 6 months postoperatively (change in mean score of 16.7 ± 3.6, P < 0.001) and at 30 months postoperatively (change in mean score of 18.9 ± 2.9, P < 0.001). Type A tympanogram was obtained in 27.8% of patients (5/18) at 6 months postoperatively, and in 77.7% at 30 months postoperatively. A Valsalva maneuver was possible in 72.2% of patients at 6 months postoperatively and in 88.9% of patients at 30 months postoperatively. In addition, the ears of 13 patients (72.2%) showed both normal tympanograms and TM at 30 months postoperatively. Interestingly, 38.5% of patients (5/13) exhibited complete sclerosis of the pars tensa. None of the patients experienced severe MWA-related complications during follow-up. CONCLUSIONS: MWA eustachian tuboplasty is a feasible alternative to conventional tuboplasty, and can improve subjective and objective outcomes in patients with ETD for up to 30 months following treatment. In addition, this study showed that the extent of sclerotic plaque increased over time, whereas the extents of atrophy and tensa retraction decreased following tuboplasty in most patients. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-82233552021-06-24 Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up Lou, Zhengcai Lou, Zihan Sun, Junzhi Chen, Zhengnong Yin, Shankai J Otolaryngol Head Neck Surg Original Research Article OBJECTIVES: This study was performed to evaluate the efficacy of microwave ablation (MWA) eustachian tuboplasty for the treatment of patients with retracted tympanic membrane (TM) due to eustachian tube dysfunction (ETD). METHODS: This was a prospective study of 20 patients with ETD (middle ear atelectasis) who underwent MWA eustachian tuboplasty. Outcomes included the ability to perform a Valsalva maneuver, audiometry results, tympanometry results, ETD Questionnaire (ETDQ-7) score, and TM status. RESULTS: Eighteen patients (18 ears) were included in this study. There were statistically and clinically significant improvements in the mean ETDQ-7 score at 6 months postoperatively (change in mean score of 16.7 ± 3.6, P < 0.001) and at 30 months postoperatively (change in mean score of 18.9 ± 2.9, P < 0.001). Type A tympanogram was obtained in 27.8% of patients (5/18) at 6 months postoperatively, and in 77.7% at 30 months postoperatively. A Valsalva maneuver was possible in 72.2% of patients at 6 months postoperatively and in 88.9% of patients at 30 months postoperatively. In addition, the ears of 13 patients (72.2%) showed both normal tympanograms and TM at 30 months postoperatively. Interestingly, 38.5% of patients (5/13) exhibited complete sclerosis of the pars tensa. None of the patients experienced severe MWA-related complications during follow-up. CONCLUSIONS: MWA eustachian tuboplasty is a feasible alternative to conventional tuboplasty, and can improve subjective and objective outcomes in patients with ETD for up to 30 months following treatment. In addition, this study showed that the extent of sclerotic plaque increased over time, whereas the extents of atrophy and tensa retraction decreased following tuboplasty in most patients. GRAPHICAL ABSTRACT: [Image: see text] BioMed Central 2021-06-24 /pmc/articles/PMC8223355/ /pubmed/34167591 http://dx.doi.org/10.1186/s40463-021-00520-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Original Research Article
Lou, Zhengcai
Lou, Zihan
Sun, Junzhi
Chen, Zhengnong
Yin, Shankai
Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up
title Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up
title_full Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up
title_fullStr Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up
title_full_unstemmed Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up
title_short Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up
title_sort microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223355/
https://www.ncbi.nlm.nih.gov/pubmed/34167591
http://dx.doi.org/10.1186/s40463-021-00520-2
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