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Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer
BACKGROUND: Ferroptosis is a newly defined form of regulated cell death characterized by the iron-dependent accumulation of lipid peroxidation and is involved in various pathophysiological conditions, including cancer. Targeting ferroptosis is considered to be a novel anti-cancer strategy. The ident...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223374/ https://www.ncbi.nlm.nih.gov/pubmed/34162423 http://dx.doi.org/10.1186/s13046-021-02012-7 |