Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer

BACKGROUND: Ferroptosis is a newly defined form of regulated cell death characterized by the iron-dependent accumulation of lipid peroxidation and is involved in various pathophysiological conditions, including cancer. Targeting ferroptosis is considered to be a novel anti-cancer strategy. The ident...

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Detalles Bibliográficos
Autores principales: Yang, Jingjing, Zhou, Yulu, Xie, Shuduo, Wang, Ji, Li, Zhaoqing, Chen, Lini, Mao, Misha, Chen, Cong, Huang, Aihua, Chen, Yongxia, Zhang, Xun, Khan, Noor Ul Hassan, Wang, Linbo, Zhou, Jichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223374/
https://www.ncbi.nlm.nih.gov/pubmed/34162423
http://dx.doi.org/10.1186/s13046-021-02012-7

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