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HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML

BACKGROUND: Leukaemia stem cells (LSCs) are responsible for the initiation, maintenance, and recurrence of acute myeloid leukaemia (AML), an aggressive haematological malignancy associated with drug resistance and relapse. Identifying therapeutic LSC targets is critical to curing AML. METHODS: Bioin...

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Detalles Bibliográficos
Autores principales: Li, Zheng, Wang, Fangce, Tian, Xiaoxue, Long, Jun, Ling, Bin, Zhang, Wenjun, Xu, Jun, Liang, Aibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223385/
https://www.ncbi.nlm.nih.gov/pubmed/34167558
http://dx.doi.org/10.1186/s13046-021-02007-4