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Neuromyelitis optica with rapid respiratory failure: a case report

BACKGROUND: Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system and is characterized by severe optic neuritis and transverse myelitis. CASE PRESENTATION: The patient was a 74‐year‐old man with pneumonia. On admission, he exhibited lower limb weakness and rapid...

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Detalles Bibliográficos
Autores principales: Otake, Kosuke, Tagami, Takashi, Kido, Norihiro, Watanabe, Akihiro, Sakamaki, Masanori, Mochizuki, Toru, Matsuda, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223450/
https://www.ncbi.nlm.nih.gov/pubmed/34194814
http://dx.doi.org/10.1002/ams2.655
Descripción
Sumario:BACKGROUND: Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system and is characterized by severe optic neuritis and transverse myelitis. CASE PRESENTATION: The patient was a 74‐year‐old man with pneumonia. On admission, he exhibited lower limb weakness and rapid respiratory deterioration in the form of tachypnea. Subsequently, he was transported to the Emergency Center of our hospital. High‐signal lesions were observed from the cervical spinal cord to the thoracic spinal cord on T2‐weighted spinal magnetic resonance images. Neuromyelitis optica was suspected, and the patient received steroid pulse therapy and immunoadsorption plasmapheresis. Serum samples obtained upon transfer were positive for anti‐aquaporin‐4 antibodies, which confirmed the diagnosis of neuromyelitis optica. Thereafter, the patient was transferred to a rehabilitation hospital. CONCLUSION: Rapid respiratory failure in neuromyelitis optica is rare, and care is needed while treating these cases.