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Neuromyelitis optica with rapid respiratory failure: a case report

BACKGROUND: Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system and is characterized by severe optic neuritis and transverse myelitis. CASE PRESENTATION: The patient was a 74‐year‐old man with pneumonia. On admission, he exhibited lower limb weakness and rapid...

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Autores principales: Otake, Kosuke, Tagami, Takashi, Kido, Norihiro, Watanabe, Akihiro, Sakamaki, Masanori, Mochizuki, Toru, Matsuda, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223450/
https://www.ncbi.nlm.nih.gov/pubmed/34194814
http://dx.doi.org/10.1002/ams2.655
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author Otake, Kosuke
Tagami, Takashi
Kido, Norihiro
Watanabe, Akihiro
Sakamaki, Masanori
Mochizuki, Toru
Matsuda, Kiyoshi
author_facet Otake, Kosuke
Tagami, Takashi
Kido, Norihiro
Watanabe, Akihiro
Sakamaki, Masanori
Mochizuki, Toru
Matsuda, Kiyoshi
author_sort Otake, Kosuke
collection PubMed
description BACKGROUND: Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system and is characterized by severe optic neuritis and transverse myelitis. CASE PRESENTATION: The patient was a 74‐year‐old man with pneumonia. On admission, he exhibited lower limb weakness and rapid respiratory deterioration in the form of tachypnea. Subsequently, he was transported to the Emergency Center of our hospital. High‐signal lesions were observed from the cervical spinal cord to the thoracic spinal cord on T2‐weighted spinal magnetic resonance images. Neuromyelitis optica was suspected, and the patient received steroid pulse therapy and immunoadsorption plasmapheresis. Serum samples obtained upon transfer were positive for anti‐aquaporin‐4 antibodies, which confirmed the diagnosis of neuromyelitis optica. Thereafter, the patient was transferred to a rehabilitation hospital. CONCLUSION: Rapid respiratory failure in neuromyelitis optica is rare, and care is needed while treating these cases.
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spelling pubmed-82234502021-06-29 Neuromyelitis optica with rapid respiratory failure: a case report Otake, Kosuke Tagami, Takashi Kido, Norihiro Watanabe, Akihiro Sakamaki, Masanori Mochizuki, Toru Matsuda, Kiyoshi Acute Med Surg Case Reports BACKGROUND: Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system and is characterized by severe optic neuritis and transverse myelitis. CASE PRESENTATION: The patient was a 74‐year‐old man with pneumonia. On admission, he exhibited lower limb weakness and rapid respiratory deterioration in the form of tachypnea. Subsequently, he was transported to the Emergency Center of our hospital. High‐signal lesions were observed from the cervical spinal cord to the thoracic spinal cord on T2‐weighted spinal magnetic resonance images. Neuromyelitis optica was suspected, and the patient received steroid pulse therapy and immunoadsorption plasmapheresis. Serum samples obtained upon transfer were positive for anti‐aquaporin‐4 antibodies, which confirmed the diagnosis of neuromyelitis optica. Thereafter, the patient was transferred to a rehabilitation hospital. CONCLUSION: Rapid respiratory failure in neuromyelitis optica is rare, and care is needed while treating these cases. John Wiley and Sons Inc. 2021-06-24 /pmc/articles/PMC8223450/ /pubmed/34194814 http://dx.doi.org/10.1002/ams2.655 Text en © 2021 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Otake, Kosuke
Tagami, Takashi
Kido, Norihiro
Watanabe, Akihiro
Sakamaki, Masanori
Mochizuki, Toru
Matsuda, Kiyoshi
Neuromyelitis optica with rapid respiratory failure: a case report
title Neuromyelitis optica with rapid respiratory failure: a case report
title_full Neuromyelitis optica with rapid respiratory failure: a case report
title_fullStr Neuromyelitis optica with rapid respiratory failure: a case report
title_full_unstemmed Neuromyelitis optica with rapid respiratory failure: a case report
title_short Neuromyelitis optica with rapid respiratory failure: a case report
title_sort neuromyelitis optica with rapid respiratory failure: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223450/
https://www.ncbi.nlm.nih.gov/pubmed/34194814
http://dx.doi.org/10.1002/ams2.655
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