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Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract

OBJECTIVES: Chondro‐osseous respiratory epithelial adenomatoid hamartomas (COREAH) are extremely rare benign lesions in the sinonasal cavity. We aim to (a) report two cases of COREAH and (b) perform a literature review with a summary on previously published cases of COREAH till August 2019. METHODS:...

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Autores principales: Yu, Yue, Tan, Chien Sheng, Koh, Leslie Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223452/
https://www.ncbi.nlm.nih.gov/pubmed/34195357
http://dx.doi.org/10.1002/lio2.580
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author Yu, Yue
Tan, Chien Sheng
Koh, Leslie Timothy
author_facet Yu, Yue
Tan, Chien Sheng
Koh, Leslie Timothy
author_sort Yu, Yue
collection PubMed
description OBJECTIVES: Chondro‐osseous respiratory epithelial adenomatoid hamartomas (COREAH) are extremely rare benign lesions in the sinonasal cavity. We aim to (a) report two cases of COREAH and (b) perform a literature review with a summary on previously published cases of COREAH till August 2019. METHODS: A literature review identified 16 cases, but only 12 cases from publications from 2005 to 2019 were included in analysis. In addition, we report two cases of COREAH from our tertiary academic medical center. RESULTS: COREAH is found in patients from 3 to 83 years old. It originates from various sites in the nasal cavity and sinuses but the most common location is the lateral nasal wall. Calcification on imaging is a common finding. CONCLUSION: COREAH is an uncommon entity that is important to recognize and distinguish from other sinister nasal masses. It is a slow growing benign lesion which lacks aggressive features on imaging. Future studies are needed to evaluate the possibility of an underlying genetic predisposition. LEVEL OF EVIDENCE: 4.
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spelling pubmed-82234522021-06-29 Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract Yu, Yue Tan, Chien Sheng Koh, Leslie Timothy Laryngoscope Investig Otolaryngol ALLERGY, RHINOLOGY, AND IMMUNOLOGY OBJECTIVES: Chondro‐osseous respiratory epithelial adenomatoid hamartomas (COREAH) are extremely rare benign lesions in the sinonasal cavity. We aim to (a) report two cases of COREAH and (b) perform a literature review with a summary on previously published cases of COREAH till August 2019. METHODS: A literature review identified 16 cases, but only 12 cases from publications from 2005 to 2019 were included in analysis. In addition, we report two cases of COREAH from our tertiary academic medical center. RESULTS: COREAH is found in patients from 3 to 83 years old. It originates from various sites in the nasal cavity and sinuses but the most common location is the lateral nasal wall. Calcification on imaging is a common finding. CONCLUSION: COREAH is an uncommon entity that is important to recognize and distinguish from other sinister nasal masses. It is a slow growing benign lesion which lacks aggressive features on imaging. Future studies are needed to evaluate the possibility of an underlying genetic predisposition. LEVEL OF EVIDENCE: 4. John Wiley & Sons, Inc. 2021-05-22 /pmc/articles/PMC8223452/ /pubmed/34195357 http://dx.doi.org/10.1002/lio2.580 Text en © 2021 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC. on behalf of The Triological Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle ALLERGY, RHINOLOGY, AND IMMUNOLOGY
Yu, Yue
Tan, Chien Sheng
Koh, Leslie Timothy
Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract
title Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract
title_full Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract
title_fullStr Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract
title_full_unstemmed Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract
title_short Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract
title_sort not just another nasal polyp: chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract
topic ALLERGY, RHINOLOGY, AND IMMUNOLOGY
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223452/
https://www.ncbi.nlm.nih.gov/pubmed/34195357
http://dx.doi.org/10.1002/lio2.580
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