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Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract
OBJECTIVES: Chondro‐osseous respiratory epithelial adenomatoid hamartomas (COREAH) are extremely rare benign lesions in the sinonasal cavity. We aim to (a) report two cases of COREAH and (b) perform a literature review with a summary on previously published cases of COREAH till August 2019. METHODS:...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223452/ https://www.ncbi.nlm.nih.gov/pubmed/34195357 http://dx.doi.org/10.1002/lio2.580 |
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author | Yu, Yue Tan, Chien Sheng Koh, Leslie Timothy |
author_facet | Yu, Yue Tan, Chien Sheng Koh, Leslie Timothy |
author_sort | Yu, Yue |
collection | PubMed |
description | OBJECTIVES: Chondro‐osseous respiratory epithelial adenomatoid hamartomas (COREAH) are extremely rare benign lesions in the sinonasal cavity. We aim to (a) report two cases of COREAH and (b) perform a literature review with a summary on previously published cases of COREAH till August 2019. METHODS: A literature review identified 16 cases, but only 12 cases from publications from 2005 to 2019 were included in analysis. In addition, we report two cases of COREAH from our tertiary academic medical center. RESULTS: COREAH is found in patients from 3 to 83 years old. It originates from various sites in the nasal cavity and sinuses but the most common location is the lateral nasal wall. Calcification on imaging is a common finding. CONCLUSION: COREAH is an uncommon entity that is important to recognize and distinguish from other sinister nasal masses. It is a slow growing benign lesion which lacks aggressive features on imaging. Future studies are needed to evaluate the possibility of an underlying genetic predisposition. LEVEL OF EVIDENCE: 4. |
format | Online Article Text |
id | pubmed-8223452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82234522021-06-29 Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract Yu, Yue Tan, Chien Sheng Koh, Leslie Timothy Laryngoscope Investig Otolaryngol ALLERGY, RHINOLOGY, AND IMMUNOLOGY OBJECTIVES: Chondro‐osseous respiratory epithelial adenomatoid hamartomas (COREAH) are extremely rare benign lesions in the sinonasal cavity. We aim to (a) report two cases of COREAH and (b) perform a literature review with a summary on previously published cases of COREAH till August 2019. METHODS: A literature review identified 16 cases, but only 12 cases from publications from 2005 to 2019 were included in analysis. In addition, we report two cases of COREAH from our tertiary academic medical center. RESULTS: COREAH is found in patients from 3 to 83 years old. It originates from various sites in the nasal cavity and sinuses but the most common location is the lateral nasal wall. Calcification on imaging is a common finding. CONCLUSION: COREAH is an uncommon entity that is important to recognize and distinguish from other sinister nasal masses. It is a slow growing benign lesion which lacks aggressive features on imaging. Future studies are needed to evaluate the possibility of an underlying genetic predisposition. LEVEL OF EVIDENCE: 4. John Wiley & Sons, Inc. 2021-05-22 /pmc/articles/PMC8223452/ /pubmed/34195357 http://dx.doi.org/10.1002/lio2.580 Text en © 2021 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC. on behalf of The Triological Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | ALLERGY, RHINOLOGY, AND IMMUNOLOGY Yu, Yue Tan, Chien Sheng Koh, Leslie Timothy Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract |
title | Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract |
title_full | Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract |
title_fullStr | Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract |
title_full_unstemmed | Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract |
title_short | Not just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract |
title_sort | not just another nasal polyp: chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract |
topic | ALLERGY, RHINOLOGY, AND IMMUNOLOGY |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223452/ https://www.ncbi.nlm.nih.gov/pubmed/34195357 http://dx.doi.org/10.1002/lio2.580 |
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